Sterilization Parameters: ultraviolet
Sterilization process parameters for medical devices, pharmaceutical equipment, and healthcare facilities. Covers ethylene oxide (EtO standard/low-temp/hospital cartridge), gamma irradiation (VDmax15, VDmax25, substantiation 25 kGy, high dose 35 kGy), electron beam, X-ray, steam autoclave (gravity 121°C, prevacuum 134°C, liquid cycle, terminal, flash, prion), hydrogen peroxide plasma/vapor (VPHP, VHP, accelerated), dry heat (150°C/170°C/HVHA), low-temperature steam formaldehyde (LTSF), ozone, UV-C, and cold plasma. Parameters include temperature, exposure time, radiation dose, gas concentration, relative humidity, sterility assurance level (SAL), material compatibility, and validation standard references.
| sterilization method | process variant | cycle pressure condition | exposure time max min (min) | exposure time min min (min) | exposure time typical min (min) | material compatibility notes | method description | notes | temperature max C (°C) | temperature min C (°C) | temperature typical C (°C) | validation standard |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ultraviolet | uvc_surface | 3-4_log_reduction_surface_only | 60 | 10 | 30 | atmospheric_ambient | UV-C germicidal irradiation (254 nm) — surface decontamination only; NOT a sterilization modality | CDC and EPA guidance for surface disinfection; ASHRAE 185.1 (HVAC UV) | 40 | 20 | 25 | Surface/air disinfection only; no penetration through materials; shadows prevent uniform treatment; used for cleanroom surfaces, water disinfection, UV-C cabinets for small items; does NOT achieve sterility for medical devices |
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